Linlin Zhang Selected Research

Remifentanil (Ultiva)

1/2022	Artesunate Reduces Remifentanil-induced Hyperalgesia and Peroxiredoxin-3 Hyperacetylation via Modulating Spinal Metabotropic Glutamate Receptor 5 in Rats.
5/2021	A Role for Transmembrane Protein 16C/Slack Impairment in Excitatory Nociceptive Synaptic Plasticity in the Pathogenesis of Remifentanil-induced Hyperalgesia in Rats.
1/2021	P2X4 receptor in the dorsal horn contributes to BDNF/TrkB and AMPA receptor activation in the pathogenesis of remifentanil-induced postoperative hyperalgesia in rats.
1/2021	NMDA Receptor Modulates Spinal Iron Accumulation Via Activating DMT1(-)IRE in Remifentanil-Induced Hyperalgesia.
1/2020	Spinal hevin mediates membrane trafficking of GluA1-containing AMPA receptors in remifentanil-induced postoperative hyperalgesia in mice.
1/2018	Spinal Protein Kinase Mζ Regulates α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Trafficking and Dendritic Spine Plasticity via Kalirin-7 in the Pathogenesis of Remifentanil-induced Postincisional Hyperalgesia in Rats.
5/2017	Involvement of Spinal PKMζ Expression and Phosphorylation in Remifentanil-Induced Long-Term Hyperalgesia in Rats.
1/2017	Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial.
1/2016	PICK1 Regulates the Expression and Trafficking of AMPA Receptors in Remifentanil-Induced Hyperalgesia.
1/2016	Involvement of CCL3/CCR5 Signaling in Dorsal Root Ganglion in Remifentanil-induced Hyperalgesia in Rats.

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Linlin Zhang Research Topics

Disease

76	Neoplasms (Cancer) 06/2022 - 12/2008
21	Hyperalgesia 01/2022 - 07/2014
19	Lung Neoplasms (Lung Cancer) 06/2022 - 01/2009
17	Pain (Aches) 01/2022 - 05/2010
12	Pre-Eclampsia (Preeclampsia) 02/2022 - 03/2013
12	Neoplasm Metastasis (Metastasis) 01/2021 - 05/2010
11	Inflammation (Inflammations) 01/2022 - 12/2013
10	Infections 01/2022 - 02/2011
9	Postoperative Pain 01/2022 - 01/2017
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 01/2014
6	Carcinogenesis 06/2022 - 01/2015
6	Neuralgia (Stump Neuralgia) 01/2022 - 05/2017
6	Fibrosis (Cirrhosis) 02/2021 - 01/2016
6	Urinary Bladder Neoplasms (Bladder Cancer) 01/2020 - 05/2006
6	Prostatic Neoplasms (Prostate Cancer) 08/2018 - 05/2009
5	Osteosarcoma (Osteogenic Sarcoma) 06/2022 - 01/2015
5	Hypersensitivity (Allergy) 01/2022 - 07/2014
5	Sepsis (Septicemia) 01/2022 - 01/2016
5	Neuroinflammatory Diseases 01/2022 - 11/2020
5	Hypertension (High Blood Pressure) 12/2021 - 01/2014
5	Breast Neoplasms (Breast Cancer) 10/2021 - 01/2014
5	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2020 - 05/2010
4	Parkinson Disease (Parkinson's Disease) 12/2022 - 01/2020
4	COVID-19 07/2022 - 01/2021
4	Acute Pain 01/2022 - 01/2018
4	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2015
4	Chronic Pain 01/2022 - 01/2016
4	Tibial Fractures (Fracture, Tibial) 01/2022 - 11/2020
4	Osteoporosis 01/2022 - 03/2017
4	Bone Fractures (Bone Fracture) 01/2022 - 01/2018
4	Delirium 12/2021 - 01/2020
4	Hyperthermia 12/2021 - 11/2015
4	Insulin Resistance 01/2021 - 12/2013
4	Carcinoma (Carcinomatosis) 01/2021 - 12/2008
4	Proteinuria 01/2021 - 01/2014
4	Hypoxia (Hypoxemia) 06/2020 - 03/2014
3	Type 2 Diabetes Mellitus (MODY) 04/2022 - 04/2016
3	Diabetes Mellitus 01/2022 - 03/2020
3	Wounds and Injuries (Trauma) 01/2022 - 07/2015
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 12/2017
3	Critical Illness (Critically Ill) 01/2022 - 01/2019
3	Acute Coronary Syndrome 01/2022 - 01/2020
3	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2018
3	Ovarian Neoplasms (Ovarian Cancer) 08/2021 - 08/2009

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 06/2022 - 02/2011
20	Pharmaceutical PreparationsIBA 01/2022 - 03/2012
17	Biomarkers (Surrogate Marker)IBA 06/2022 - 01/2014
11	Biological ProductsIBA 06/2022 - 05/2015
11	Remifentanil (Ultiva)FDA Link 01/2022 - 01/2015
11	Messenger RNA (mRNA)IBA 05/2021 - 08/2009
10	MicroRNAs (MicroRNA)IBA 08/2021 - 01/2015
10	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 03/2012
8	CateninsIBA 02/2022 - 12/2012
7	Antineoplastic Agents (Antineoplastics)IBA 06/2022 - 10/2012
7	CytokinesIBA 01/2022 - 01/2016
7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 07/2016
7	Small Interfering RNA (siRNA)IBA 01/2021 - 02/2015
6	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2021 - 01/2015
6	AMPA Receptors (AMPA Receptor)IBA 01/2021 - 01/2016
6	AcidsIBA 10/2020 - 01/2016
6	fu-yuanIBA 01/2020 - 01/2009
6	Silicon Dioxide (Silica)FDA LinkGeneric 01/2019 - 03/2012
5	MetalsIBA 01/2022 - 10/2016
5	Hypoglycemic Agents (Hypoglycemics)IBA 01/2022 - 04/2016
5	LipidsIBA 01/2021 - 01/2015
5	Caspase 3 (Caspase-3)IBA 01/2021 - 05/2006
4	Peptide Hydrolases (Proteases)FDA Link 07/2022 - 01/2020
4	AntioxidantsIBA 01/2022 - 08/2006
4	Analgesics (Analgesic Drugs)IBA 01/2022 - 01/2018
4	Opioid Analgesics (Opioids)IBA 01/2021 - 07/2014
4	Long Noncoding RNAIBA 01/2021 - 01/2019
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 09/2012
4	LipopolysaccharidesIBA 10/2019 - 01/2016
4	Phosphotransferases (Kinase)IBA 01/2018 - 11/2015
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 12/2013
4	NanocapsulesIBA 01/2017 - 12/2011
4	ManganeseIBA 10/2016 - 12/2011
4	Histone Deacetylase 6IBA 01/2016 - 11/2013
3	Immune Checkpoint InhibitorsIBA 06/2022 - 01/2022
3	dichlorobis(azomycin)platinum IIIBA 01/2022 - 01/2018
3	HydrogenIBA 01/2022 - 10/2019
3	ArtesunateIBA 01/2022 - 01/2022
3	Clopidogrel (Plavix)FDA Link 01/2022 - 04/2015
3	CaspasesIBA 01/2022 - 05/2006
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 01/2020
3	RNA (Ribonucleic Acid)IBA 01/2022 - 08/2018
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2018
3	salicylhydroxamic acid (SHAM)IBA 01/2022 - 01/2016
3	Contrast MediaIBA 12/2021 - 12/2011
3	Angiotensin IIIBA 02/2021 - 01/2017

Therapy/Procedure

34	Therapeutics 06/2022 - 12/2008
15	Drug Therapy (Chemotherapy) 12/2022 - 08/2011
8	Precision Medicine 01/2021 - 03/2012
4	Immunotherapy 04/2022 - 01/2019
4	Orthopedic Procedures 01/2022 - 11/2020
4	Length of Stay 01/2022 - 01/2018
4	Spinal Injections 01/2022 - 01/2016
4	Radiotherapy 09/2021 - 05/2010
4	Critical Care (Surgical Intensive Care) 01/2021 - 10/2013
4	Stents 11/2018 - 04/2015